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Review
. 2014 Jun;41(6):3915-23.
doi: 10.1007/s11033-014-3259-6. Epub 2014 Feb 19.

Regulatory non-coding RNAs: revolutionizing the RNA world

Biao Huang  1 , Rongxin Zhang
Affiliations
Review

Regulatory non-coding RNAs: revolutionizing the RNA world

Biao Huang et al. Mol Biol Rep. 2014 Jun.

Abstract

The majority of the genomic DNA sequence in mammalian and other higher organisms can be transcribed into abundant functional RNA transcripts, especially regulatory non-coding RNAs (ncRNAs) that are expressed in a developmentally and species-specific regulated manner. Here, we review various regulatory non-coding RNAs, including regulatory small non-coding RNAs (sncRNAs) and long non-coding RNAs (lncRNAs), and summarize two and eight kinds of distinct modes of action for sncRNAs and lncRNAs respectively, by which functional ncRNAs mediate the regulation of intracellular events.

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