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. 2014 May 21;26(19):3124-30.
doi: 10.1002/adma.201305506. Epub 2014 Feb 18.

3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs

David B Kolesky  1 , Ryan L Truby, A Sydney Gladman, Travis A Busbee, Kimberly A Homan, Jennifer A Lewis
Affiliations

3D bioprinting of vascularized, heterogeneous cell-laden tissue constructs

David B Kolesky et al. Adv Mater. .

Abstract

A new bioprinting method is reported for fabricating 3D tissue constructs replete with vasculature, multiple types of cells, and extracellular matrix. These intricate, heterogeneous structures are created by precisely co-printing multiple materials, known as bioinks, in three dimensions. These 3D micro-engineered environments open new -avenues for drug screening and fundamental studies of wound healing, angiogenesis, and stem-cell niches.

Keywords: 3D printing; biomaterials; bioprinting; tissue engineering; vasculature.

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