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. 2013 Nov;29(6):1354-7.

Age - specific incidence rate change at breast Cancer and its different histopathologic subtypes in Iran and Western countries

Maryam Sadat Hosseini  1 , Maliheh Arab  1 , Behzad Nemati Honar  2 , Giti Noghabaei  3 , Nazanin Safaei  4 , Tahereh Ghasemi  5 , Farah Farzaneh  6 , Tahereh Ashraf Ganjoie  7
Affiliations

Age - specific incidence rate change at breast Cancer and its different histopathologic subtypes in Iran and Western countries

Maryam Sadat Hosseini et al. Pak J Med Sci. 2013 Nov.

Abstract

Objective: The aim of the present study was to determine the frequency and age-specific incidence rate of different histopathologic subtypes of breast cancer in Iran, and compare it to neighboring and Western countries and to discuss the probable effective main factors.

Methods: National data from cancer registry for 6265 female breast cancer patients were studied in 10 histopathologic groups.

Results: The most common tumor was ductal carcinoma (89%). The peak age - specific incidence rate of breast cancer in total, and for epithelial, non-epithelial and ductal carcinomas were all 50-59 years, and it decreased in older age. It is in contrast to US SEER report which shows the incidence increases in higher age.

Conclusion: Three main factors including younger age of Iranian patients, probable more ERN tumors and different histopathological profile of breast cancer in Iran might be considered and studied to explain different slope of breast cancer after menopause compared to other countries.

Keywords: Age groups; Breast cancer; Histopathology; Incidence.

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Figures

Fig.1
Fig.1
Comparison of age–specific incidence rate of breast cancer in Iran, Iraq and US
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References

    1. Althuis MD, Dozier JM, Anderson WF, Devesa SS, Brinton LA. Global trends in breast cancer incidence and mortality 1973-97. Int J Epidemiol. 2005;34:405–412. - PubMed
    1. Toi M, Ohashi Y, Seow A, Moriya T, Tse G, Sasano H, et al. The breast cancer working group presentation divided into three sections: the epidemiology, pathology and treatment of breast cancer. Jpn J Clin Oncol. 2010;40(Suppl 1):i13–18. - PubMed
    1. Rennert G. Breast cancer. In: Freedmanls EB, Ries LAG, Young JL, editors. Cancer Incidence in Four Member Countries of the MECC Compared with US SEER. National Cancer Institute MECC Monograph; 2006. pp. 73–81.
    1. Anderson WF, Chu KC, Chang S, Sherman ME. Comparison of Age- specific incidence rate patterns for different histopathologic types of breast carcinoma. Cancer epidermiol Biomarkers Prev. 2004;13(7):1128–1136. - PubMed
    1. Nixon AJ, Neuberg D, Hayes DF. Relationship of patient age to pathologic features of the tumor and prognosis for patients with stage I or ii breast cancer. J Clin Oncol. 1994;12:888–894. - PubMed

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