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Case Reports
. 2014 Jan 15;7(2):835-9.
eCollection 2014.

Skin erythema with leukocytoclastic vasculitis and elastophagocytosis as the presenting features of an underlying myelodysplastic syndrome

Mitsuaki Ishida  1 , Hiroko Okuno  2 , Miyuki Yoshii  2 , Akiko Horinouchi  2 , Ayaka Shirakawa  2 , Ayumi Harada  2 , Muneo Iwai  3 , Keiko Yoshida  3 , Akiko Kagotani  3 , Takashi Yoshida  2 , Hidetoshi Okabe  1
Affiliations
Case Reports

Skin erythema with leukocytoclastic vasculitis and elastophagocytosis as the presenting features of an underlying myelodysplastic syndrome

Mitsuaki Ishida et al. Int J Clin Exp Pathol. .
No abstract available

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Figures

Figure 1
Figure 1
Histopathological features of the knee showing leukocytoclastic vasculitis and elastophagocytosis. A: Lymphocytes and neutrophils have infiltrated around the vessels of the superficial dermis. HE, x 100. B: Nuclear dust and fibrinoid necrosis of the vessels are observed. HE, x 400. C: Superficial perivascular lymphocytic infiltration and interstitial histiocytic infiltration. HE, x 100. D: Histiocytic infiltration into the superficial dermis. HE, x 400. Elastica van Gieson staining clearly showing elastophagocytosis (inset, x 400).
Figure 2
Figure 2
Immunohistochemical findings of the knee. CD3-positive lymphocytes are predominant, and a few infiltrating CD20-positive T-cells are observed, x 400.
Figure 3
Figure 3
Histopathological and immunohistochemical features of the bone marrow. Hypercellular bone marrow with increase of blastic cells. HE, x 400. Most of the blastic cells are positive for c-kit. x 400.
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References

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