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Case Reports
. 2014 Jan 15;7(2):835-9.
eCollection 2014.

Skin erythema with leukocytoclastic vasculitis and elastophagocytosis as the presenting features of an underlying myelodysplastic syndrome

Mitsuaki Ishida  1 , Hiroko Okuno  2 , Miyuki Yoshii  2 , Akiko Horinouchi  2 , Ayaka Shirakawa  2 , Ayumi Harada  2 , Muneo Iwai  3 , Keiko Yoshida  3 , Akiko Kagotani  3 , Takashi Yoshida  2 , Hidetoshi Okabe  1
Affiliations
Case Reports

Skin erythema with leukocytoclastic vasculitis and elastophagocytosis as the presenting features of an underlying myelodysplastic syndrome

Mitsuaki Ishida et al. Int J Clin Exp Pathol. .
No abstract available

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Figures

Figure 1
Figure 1
Histopathological features of the knee showing leukocytoclastic vasculitis and elastophagocytosis. A: Lymphocytes and neutrophils have infiltrated around the vessels of the superficial dermis. HE, x 100. B: Nuclear dust and fibrinoid necrosis of the vessels are observed. HE, x 400. C: Superficial perivascular lymphocytic infiltration and interstitial histiocytic infiltration. HE, x 100. D: Histiocytic infiltration into the superficial dermis. HE, x 400. Elastica van Gieson staining clearly showing elastophagocytosis (inset, x 400).
Figure 2
Figure 2
Immunohistochemical findings of the knee. CD3-positive lymphocytes are predominant, and a few infiltrating CD20-positive T-cells are observed, x 400.
Figure 3
Figure 3
Histopathological and immunohistochemical features of the bone marrow. Hypercellular bone marrow with increase of blastic cells. HE, x 400. Most of the blastic cells are positive for c-kit. x 400.
See this image and copyright information in PMC

References

    1. Brunning RD, Orazi A, Germing U, Le Beau MM, Porwit A, Baumann I, Vardiman JW, Hellstrom-Lindberg E. Myelodysplastic syndromes/neoplasms, overview. In: Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW, editors. World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC Press; 2008. pp. 88–93.
    1. Farah C, Livideanu CB, Jegu J, Paul C, Viraben R, Lamant R, Delavigne K, Adoue D, Laurent G, Beyne Rauzy O. Prevalence and prognostic value of cutaneous manifestations in patients with myelodysplastic syndrome. J Eur Acad Dermatol Venereol. 2010;24:1171–1175. - PubMed
    1. Dalamaga M, Karmaniolas K, Matekovits A, Migdalis I, Papadavid E. Cutaneous manifestations in relation to immunologic parameters in a cohort of primary myelodysplastic syndrome patients. J Eur Acad Dermatol Venereol. 2008;22:543–548. - PubMed
    1. Watson KM, Mufti G, Salisburg JR, du Vivier AW, Creamer D. Spectrum of clinical presentation, treatment and prognosis in a series of eight patients with leukaemia cutis. Clin Exp Dermatol. 2006;31:218–221. - PubMed
    1. Morand JJ, Lightburn E, Richard MA, Hesse-Bonerandi S, Carsuzaa F, Grob JJ. Skin manifestations associated with myelodysplastic syndromes. Rev Med Interne. 2001;22:845–853. - PubMed

Supplementary concepts

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