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Case Reports
. 2014 Mar;30(1):45-7.
doi: 10.1007/s12288-012-0185-4. Epub 2012 Aug 28.

Paediatric T cell Lymphoma with Nephrotic Syndrome: A Rare Association

Deepa Joseph  1 , Dubashi Biswajit  2 , Rajesh Nachiappa Ganesh  3 , Sreejith Parameswaran  4 , Ankit Jain  2
Affiliations
Case Reports

Paediatric T cell Lymphoma with Nephrotic Syndrome: A Rare Association

Deepa Joseph et al. Indian J Hematol Blood Transfus. 2014 Mar.

Abstract

Renal involvement is frequent in hematologic malignancies especially Hodgkin's lymphoma. Renal complications in children with malignancies primarily arise from tumour lysis syndrome, malignant infiltration or obstruction of the urinary tract, deposits of immunoglobulin fractions or crystals, renal infiltration by malignant cells, paraneoplastic or storage glomerulopathies. Nephrotic syndrome has been described in B cell type Non Hodgkin's lymphomas. There are very few reports of association of T cell lymphoma and nephrotic syndrome in pediatric patients. We present a case of peripheral T cell lymphoma with nephrotic syndrome in a 10 year old boy.

Keywords: Nephrotic syndrome; PTCL; Pediatric Lymphoma.

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Figures

Fig. 1
Fig. 1
a Sections shows single linear core of kidney biopsy with normal light microscopic histology of glomerular, tubular, interstitial and vascular compartments. Masson Trichrome stain, ×40. b Sections show glomeruli with normal capillary membrane thickness and cellularity and unremarkable tubules, PAS stain, ×400
See this image and copyright information in PMC

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