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. 2014 Mar;202(3):W217-23.
doi: 10.2214/AJR.13.11733.

Molecular imaging of pulmonary nodules

Anna Margherita Maffione  1 , Gaia Grassetto, Lucia Rampin, Sotirios Chondrogiannis, Maria Cristina Marzola, Valentina Ambrosini, Domenico Rubello
Affiliations

Molecular imaging of pulmonary nodules

Anna Margherita Maffione et al. AJR Am J Roentgenol. 2014 Mar.

Abstract

Objective: Lung nodules can be benign or malignant, reflecting many possible causes, ranging from inflammatory and infectious processes to neoplasms. Incidental detection on chest x-ray or thoracic CT often requires further evaluation by imaging or invasive procedures.

Conclusion: Currently, 18F-FDG PET/CT offers both anatomic and metabolic characterization of lung nodules. Fluorine-18-thymidine, 11C-methionine, 68Ga-DOTA-somatostatin analogs, and 18F-dihydroxyphenylalanine may offer additional molecular information useful for diagnosis and treatment planning.

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