Wolfram syndrome iPS cells: the first human cell model of endoplasmic reticulum disease
- PMID: 24556864
- PMCID: PMC3931391
- DOI: 10.2337/db13-1809
Wolfram syndrome iPS cells: the first human cell model of endoplasmic reticulum disease
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β-cell dysfunction due to increased ER stress in a stem cell model of Wolfram syndrome.Diabetes. 2014 Mar;63(3):923-33. doi: 10.2337/db13-0717. Epub 2013 Nov 13. Diabetes. 2014. PMID: 24227685 Free PMC article.
References
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- Barrett TG, Bundey SE, Macleod AF. Neurodegeneration and diabetes: UK nationwide study of Wolfram (DIDMOAD) syndrome. Lancet 1995;346:1458–1463 - PubMed
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- Fonseca SG, Fukuma M, Lipson KL, et al. WFS1 is a novel component of the unfolded protein response and maintains homeostasis of the endoplasmic reticulum in pancreatic beta-cells. J Biol Chem 2005;280:39609–39615 - PubMed
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