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. 2012:2012:978170.
doi: 10.1155/2012/978170. Epub 2012 Nov 22.

An unusual cardiac manifestation in autosomal dominant polycystic kidney disease

Fausta Catapano  1 , Stefano Pancaldi  2 , Carlo Pace Napoleone  3 , Lucia Barbara De Sanctis  1 , Gaetano Gargiulo  3 , Giuseppe Emiliani  4 , Antonio Santoro  1
Affiliations

An unusual cardiac manifestation in autosomal dominant polycystic kidney disease

Fausta Catapano et al. Case Rep Nephrol. 2012.

Abstract

Autosomal dominant polycystic kidney disease is a common hereditary disorder characterized by renal and extrarenal, cystic and noncystic manifestations. Connective tissue defects, including cerebral aneurysm, meningeal diverticula, abdominal wall hernias, intestinal diverticula, and cardiac valvular abnormalities, are widely known manifestations. Instead intracardiac aneurysms have never been reported in adults with autosomal dominant polycystic kidney disease. We describe a 65-year-old patient with end-stage renal disease due to autosomal dominant polycystic kidney disease and an atrial septum aneurysm associated with platypnoea-orthodeoxia syndrome.

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Figures

Figure 1
Figure 1
(a) Chest X-ray showing the elevation of the right diaphragm; (b) abdomen multislices CT-scan view showing the hepatic and kidney cysts.
Figure 2
Figure 2
Transesophageal echocardiogram demonstrating: (a) the aneurysm of the atrial septum (white arrow) and (b) the size of patent foramen ovale (0.8 cm) with right-to-left shunting (black arrow) after agitated saline contrast injection. RA, right atrium; LA, left atrium.
See this image and copyright information in PMC

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