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Review
. 2014 Mar;101(3):633-4.
doi: 10.1016/j.fertnstert.2013.12.032.

Female age-related fertility decline. Committee Opinion No. 589

American College of Obstetricians and Gynecologists Committee on Gynecologic Practice and Practice Committee
Free article
Review

Female age-related fertility decline. Committee Opinion No. 589

American College of Obstetricians and Gynecologists Committee on Gynecologic Practice and Practice Committee. Fertil Steril. 2014 Mar.
Free article

Abstract

The fecundity of women decreases gradually but significantly beginning approximately at age 32 years and decreases more rapidly after age 37 years. Education and enhanced awareness of the effect of age on fertility are essential in counseling the patient who desires pregnancy. Given the anticipated age-related decline in fertility, the increased incidence of disorders that impair fertility, and the higher risk of pregnancy loss, women older than 35 years should receive an expedited evaluation and undergo treatment after 6 months of failed attempts to conceive or earlier, if clinically indicated. In women older than 40 years, more immediate evaluation and treatment are warranted.

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