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. 1988;178(2):137-42.
doi: 10.1007/BF02463647.

Ultrastructural localisation of serotonin and substance P in vascular endothelial cells of rat femoral and mesenteric arteries

A Loesch  1 , G Burnstock
Affiliations

Ultrastructural localisation of serotonin and substance P in vascular endothelial cells of rat femoral and mesenteric arteries

A Loesch et al. Anat Embryol (Berl). 1988.

Abstract

An electron microscopic-immunocytochemical study has been made on the localisation of serotonin and substance P in endothelial cells of femoral and mesenteric arteries of the rat. In the femoral and mesenteric arteries, less than 10% of the endothelial cells showed positive immunolabelling for these substances. The distribution of serotonin and substance P in endothelial cells was similar in both arteries. The immunoprecipitate was confined to the cytoplasm, including subcellular organelles. The results are discussed in terms of endothelial mechanisms of local control of blood flow.

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References

    1. J Cardiovasc Pharmacol. 1987;10 Suppl 12:S74-81 - PubMed
    1. Circ Res. 1983 Nov;53(5):557-73 - PubMed
    1. Neuroscience. 1987 Aug;22(2):413-23 - PubMed
    1. J Comp Neurol. 1985 May 8;235(2):268-76 - PubMed
    1. Nature. 1980 Nov 27;288(5789):373-6 - PubMed