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Comment
. 2014 Apr;11(4):205-7.
doi: 10.1038/nrgastro.2014.25. Epub 2014 Feb 25.

NAFLD. Metabolic make-up of NASH: from fat and sugar to amino acids

Silvia Sookoian  1 , Carlos J Pirola  2
Affiliations
Comment

NAFLD. Metabolic make-up of NASH: from fat and sugar to amino acids

Silvia Sookoian et al. Nat Rev Gastroenterol Hepatol. 2014 Apr.

Abstract

NAFLD is regarded unquestionably as one of the components of the metabolic syndrome. Hence, metabolic perturbations occurring in the fatty liver become a systemic metabolic derangement. The phenotypic switching from fatty liver to NASH entails a reprogramming of liver metabolism to fit a stressful metabolic environment.

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