Tonsillitis and respiratory infections of viral aetiology in a developing country

Abstract

Among 75 clinically diagnosed cases of tonsillitis, 55 (73.3%) were found to be of viral aetiology. Serological and virological investigations identified adenovirus as the main causative agent in children as well as in adults. In only two instances, both in children, was an association with respiratory syncytial virus (RSV) in tonsillitis detected, an extremely rare finding. A cross-sectional sero-epidemiological study of respiratory infections caused by adenovirus, RSV, influenza (A,B) and para-influenza (types 1,2,3) viruses was carried out in 289 Saudi children (newborn to 15 years of age) and 86 adults (healthy male blood donors and pregnant women) using a single serological technique. In children as well as in adults, adenoviruses were the most predominant respiratory pathogens, with no marked variation in age-specific antibody prevalence rates.