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Case Reports
. 2014 Mar;63(3):225-30.
doi: 10.1007/s00101-014-2297-8. Epub 2014 Feb 27.

[Overwhelming postsplenectomy infection syndrome]

[Article in German]
C Fuchs  1 , C Scheer, K Schulz, F Dombrowski, S Brückmann, S-O Kuhn
Affiliations
Case Reports

[Overwhelming postsplenectomy infection syndrome]

[Article in German]
C Fuchs et al. Anaesthesist. 2014 Mar.

Abstract

The overwhelming postsplenectomy infection syndrome (OPSI) is a fulminant sepsis that is mainly caused by Streptococcus pneumoniae and is characterized by a particular high mortality. Patients whose spleen was removed due to a hematological disease are at special risk. Even after the recommended immunization against Streptococcus pneumoniae 20-30 % of these patients do not develop an adequate level of antibody response. Therefore, this particular group of patients must be trained how to behave in case of fever and need to obtain immediate specific sepsis therapy with antibiotic prophylaxis.

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