Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Feb;47(1):55-8.
doi: 10.5090/kjtcs.2014.47.1.55. Epub 2014 Feb 5.

Mixed squamous cell and glandular papilloma of the lung in a 64-year-old woman

Affiliations
Case Reports

Mixed squamous cell and glandular papilloma of the lung in a 64-year-old woman

Ju Sik Yun et al. Korean J Thorac Cardiovasc Surg. 2014 Feb.

Abstract

Mixed squamous cell and glandular papilloma of the lung is an extremely rare benign epithelial tumor showing a mixture of squamous and glandular epithelium. Here, we report a case of mixed squamous cell and glandular papilloma that presented as a solitary nodule in the left lower lobe of a 64-year-old woman. Chest computed tomography demonstrated a lobulated mass in the basal segment of the left lower lobe. The patient underwent a lobectomy under the suspicion of lung malignancy. The histopathological diagnosis was mixed squamous cell and glandular papilloma.

Keywords: Lung neoplasms; Mixed squamous cell and glandular papilloma; Papilloma.

PubMed Disclaimer

Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
(A) Chest X-ray shows a nodule (arrow) in the left lower lung field. (B) Chest computed tomography scan shows 4×3 cm lobulated nodule in the basal segment of the left lower lobe. (C) Further, a positron emission tomography scan shows increased uptake (maximal standardized uptake value of 6.7) in these nodular lesions.
Fig. 2
Fig. 2
Pathological findings. (A) Mixed squamous and mucin-secreting glandular epithelium covered the fibrovascular cores (H&E, ×20), (B) mucin-secreting glandular epitheliums (H&E, ×1,000), and (C) acantholytic squamous epithelial nests (H&E, ×1,000), and immunohistochemical staining. (D) The tumor cells were positive for p63.

References

    1. Flieder DB, Thivolet-Bejui F, Popper H. Mixed squamous cell and glandular papilloma. In: Travis WD, Brambilla E, Muller-Hermelink HK, Harris CC, editors. Pathology and genetics: tumours of the lung, pleura, thymus, and heart. Lyon: IARC Press; 2004. pp. 78–81.
    1. Tryfon S, Dramba V, Zoglopitis F, et al. Solitary papillomas of the lower airways: epidemiological, clinical, and therapeutic data during a 22-year period and review of the literature. J Thorac Oncol. 2012;7:643–648. - PubMed
    1. Abiko T, Koizumi S, Takanami I, Tanaka F. 18F-FDG-PET/CT findings in primary pulmonary mixed squamous cell and glandular papilloma. Ann Nucl Med. 2011;25:227–229. - PubMed
    1. Sung CO, Kim J, Do IG, Han J. Solitary pulmonary mixed squamous cell and glandular papilloma: a brief case report. Korean J Pathol. 2008;42:393–395.
    1. Kadota K, Haba R, Katsuki N, et al. Cytological findings of mixed squamous cell and glandular papilloma in the lung. Diagn Cytopathol. 2010;38:913–917. - PubMed

Publication types

LinkOut - more resources