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. 2012 Dec;1(1):19-24.
doi: 10.3978/j.issn.2304-3881.2012.07.02.

Diagnosis and treatment of hepatic angiomyolipoma

Shunda Du  1 , Ying Li  1 , Yilei Mao  1 , Xinting Sang  1 , Xin Lu  1 , Wenze Wang  2 , Qing Zhang  3 , Huadan Xue  4 , Xiaobo Yang  1 , Shaohua Li  1 , Tianyi Chi  1 , Shouxian Zhong  1 , Jiefu Huang  1
Affiliations

Diagnosis and treatment of hepatic angiomyolipoma

Shunda Du et al. Hepatobiliary Surg Nutr. 2012 Dec.

Abstract

Background: Hepatic angiomyolipoma (HAML) is a rare liver tumor. This paper summarized the clinical, radiological and pathological features of HAML.

Methods: Seventeen cases of HAML were analyzed retrospectively. All patients were subjected to surgical resection of tumor, one of which was performed emergency surgery because of hemorrhage of tumor.

Results: There are 13 females and 4 males, most of whom were asymptotic except 4 had minimal abdominal discomfort. US, CT and/or MRI were taken and corresponding data was comprehensively analyzed with other clinical signs and symptoms. Correct preoperative diagnosis was able to be achieved in 9 patients. Pathological analysis and immunohistochemistry of HMB-45 was used as final diagnosis. All patients were followed up and survived without recurrence.

Conclusions: Preoperative diagnosis of HAML can be benefited from comprehensive analysis of clinical manifestations. The malignant potential and fast growth of tumor suggested surgical removal of tumor while it was diagnosed.

Keywords: Hepatic tumor; angiomyolipoma; diagnosis; surgery.

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Figures

Figure 1
Figure 1
A. One hyperechoic nodule of 4.6 cm × 3.9 cm in size was seen in the right hepatic region. The lesion exhibited clear border, uneven echo, and reticular structure; B. Abundant arterial blood flow signal with regular distribution were observed
Figure 2
Figure 2
A. A lesion of mixed density was visible in right hepatic region with a size of 10.7 cm × 10.6 cm × 9.9 cm. It has smooth edge, of low density and flocky. CT value -34 to 21HU; B, C, D. Enhanced arterial phase scan shows heterogeneous enhancement with strengthened portal and delayed phases
Figure 3
Figure 3
Pathology showed blood vessels, smooth muscle cells and adipose tissue. A. haematoxylin & eosin; B. HBM45 staining positive
See this image and copyright information in PMC

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