doi: 10.1002/adhm.201300479.
Epub 2013 Oct 30.
Electrochemical control of the enzymatic polymerization of PEG hydrogels: formation of spatially controlled biological microenvironments
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- PMID: 24574303
- DOI: 10.1002/adhm.201300479
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Electrochemical control of the enzymatic polymerization of PEG hydrogels: formation of spatially controlled biological microenvironments
Adv Healthc Mater.
2014 Apr.
Abstract
Control of pH gradient profile at the electrode-electrolyte interfaces allows the control of the enzymatic PEG-hydrogel polymerization. By tuning the solution pH, buffer capacity, and the applied current, the extent of the local inhibition and confinement of the Factor XIII-mediated polymerization of PEG are controlled. This technology opens new perspectives for the production of 3D-structured biological microenvironments.
Keywords: PEG-hydrogels; electrochemistry; microenvironment.
© 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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