Review
doi: 10.4103/0970-9185.125685.
Considerations in perioperative assessment of valproic acid coagulopathy
Affiliations
- PMID: 24574585
- PMCID: PMC3927296
- DOI: 10.4103/0970-9185.125685
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Review
Considerations in perioperative assessment of valproic acid coagulopathy
J Anaesthesiol Clin Pharmacol.
2014 Jan.
Abstract
Valproic acid (VPA) is one of the widely prescribed antiepileptic drugs in children with multiple indications. VPA-induced coagulopathy may occur and constitute a pharmacological and practical challenge affecting pre-operative evaluation and management of patients receiving VPA therapy. This review summarizes the different studies documenting the incidence, severity and available recommendations related to this adverse effect.
Keywords: Adverse effects; anesthesia; coagulation disorders; perioperative care; valproic acid.
Conflict of interest statement
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