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Review
. 2014 Jan;30(1):7-9.
doi: 10.4103/0970-9185.125685.

Considerations in perioperative assessment of valproic acid coagulopathy

Claude Abdallah  1
Affiliations
Review

Considerations in perioperative assessment of valproic acid coagulopathy

Claude Abdallah. J Anaesthesiol Clin Pharmacol. 2014 Jan.

Abstract

Valproic acid (VPA) is one of the widely prescribed antiepileptic drugs in children with multiple indications. VPA-induced coagulopathy may occur and constitute a pharmacological and practical challenge affecting pre-operative evaluation and management of patients receiving VPA therapy. This review summarizes the different studies documenting the incidence, severity and available recommendations related to this adverse effect.

Keywords: Adverse effects; anesthesia; coagulation disorders; perioperative care; valproic acid.

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Conflict of interest statement

Conflict of Interest: None declared.

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