Betel nut usage is a major risk factor for coronary artery disease
- PMID: 24576380
- PMCID: PMC4825463
- DOI: 10.5539/gjhs.v6n2p189
Betel nut usage is a major risk factor for coronary artery disease
Abstract
Aim: The objective of our study was to assess betel nut usage as one of the major risk factors associated with coronary artery disease.
Methods: This case control study consisted of 300 controls and 300 cases. A structured questionnaire was administered to the participants to assess consumption of betel nut and confounding variables. A respondent was considered a regular consumer of betel nut if he/she consumed one or more pieces of betel nut every day for a period of greater than 6 months.
Results: About 8 in 10 betel nut chewers developed coronary artery disease. After adjusting for diabetes and hypertension, the odds ratio analysis depicted 7.72 times greater likelihood for coronary artery disease in patients who chewed betel nut for more than 10 years.
Conclusion: Our study concludes that betel nut chewing is a significant risk factor leading to the development of coronary artery disease.
Similar articles
-
Chewing areca nut increases the risk of coronary artery disease in Taiwanese men: a case-control study.BMC Public Health. 2012 Mar 7;12:162. doi: 10.1186/1471-2458-12-162. BMC Public Health. 2012. PMID: 22397501 Free PMC article.
-
Epidemiology of areca (betel) nut use in the mariana islands: Findings from the University of Guam/University of Hawai`i cancer center partnership program.Cancer Epidemiol. 2017 Oct;50(Pt B):241-246. doi: 10.1016/j.canep.2017.08.006. Cancer Epidemiol. 2017. PMID: 29120831 Free PMC article.
-
Betel nut chewing is associated with increased risk of cardiovascular disease and all-cause mortality in Taiwanese men.Am J Clin Nutr. 2008 May;87(5):1204-11. doi: 10.1093/ajcn/87.5.1204. Am J Clin Nutr. 2008. PMID: 18469240
-
Betel nut chewing and the risk of chronic kidney disease: evidence from a meta-analysis.Int Urol Nephrol. 2018 Jun;50(6):1097-1104. doi: 10.1007/s11255-018-1819-8. Epub 2018 Feb 13. Int Urol Nephrol. 2018. PMID: 29441477 Review.
-
Oral lichenoid contact lesions induced by areca nut and betel quid chewing: a mini review.J Investig Clin Dent. 2012 Aug;3(3):163-6. doi: 10.1111/j.2041-1626.2012.00130.x. J Investig Clin Dent. 2012. PMID: 22887903 Review.
Cited by
-
Molecular Mechanisms of Malignant Transformation of Oral Submucous Fibrosis by Different Betel Quid Constituents-Does Fibroblast Senescence Play a Role?Int J Mol Sci. 2022 Jan 31;23(3):1637. doi: 10.3390/ijms23031637. Int J Mol Sci. 2022. PMID: 35163557 Free PMC article. Review.
-
Barriers to Quitting Areca Nut Consumption and Joining a Cessation Program as Perceived by Chewer and Nonchewer Populations in Guam.Subst Use Misuse. 2020;55(6):947-953. doi: 10.1080/10826084.2020.1716012. Epub 2020 Jan 24. Subst Use Misuse. 2020. PMID: 31973623 Free PMC article.
-
Diagonal Earlobe Crease as a Significant Marker for Coronary Artery Disease: A Case-control Study.Cureus. 2017 Feb 5;9(2):e1013. doi: 10.7759/cureus.1013. Cureus. 2017. PMID: 28331775 Free PMC article.
-
Betel Nut Chewing Was Associated with Obstructive Lung Disease in a Large Taiwanese Population Study.J Pers Med. 2021 Sep 28;11(10):973. doi: 10.3390/jpm11100973. J Pers Med. 2021. PMID: 34683114 Free PMC article.
-
Areca Nut Chewing and the Risk of Re-hospitalization and Mortality Among Patients With Acute Coronary Syndrome in Pakistan.J Prev Med Public Health. 2018 Mar;51(2):71-82. doi: 10.3961/jpmph.17.189. J Prev Med Public Health. 2018. PMID: 29631348 Free PMC article.
References
-
- Accortt N. A, Waterbor J. W, Beall C, Howard G. Chronic disease mortality in a cohort of smokeless tobacco users. Am J Epidemiol. 2002;156:730–737. http://dx.doi.org/10.1093/aje/kwf106 . - PubMed
-
- Boffetta P, Straif K. Use of smokeless tobacco and risk of myocardial infarction and stroke: systematic review with meta-analysis. BMJ. 2009;339:3060. http://dx.doi.org/10.1136/bmj.b3060 . - PMC - PubMed
-
- Bolinder G, Alfredsson L, Englund A, de Faire U. Smokeless tobacco use and increased cardiovascular mortality among Swedish construction workers. Am J Public Health. 1994;84:399–404. http://dx.doi.org/10.2105/AJPH.84.3.399 . - PMC - PubMed
-
- Boucher B. J, Mannan N. Metabolic effects of the consumption of Areca catechu. Addict Biol. 2002;7:103–10. http://dx.doi.org/10.1080/13556210120091464 . - PubMed
-
- Chang L. Y, Wan H. C, Lai Y. L, Kuo Y. F, Liu T. Y, Chen Y. T. Areca nut extracts increased expression of inflammatory cytokines, tumor necrosis factor-α, interleukin-1β, interleukin-6 and interleukin-8, in peripheral blood mononuclear cells. J Periodontal Res. 2009;44(2):175–83. http://dx.doi.org/10.1111/j.1600-0765.2008.01104.x . - PubMed
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical