Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2013 Aug;15(8):729-33.
doi: 10.5812/ircmj.4415. Epub 2013 Aug 5.

Frequency of rotavirus and adenovirus gastroenteritis among children in shiraz, iran

Mohammad Motamedifar  1 , Elham Amini  2 , Pedram Talezadeh Shirazi  2
Affiliations

Frequency of rotavirus and adenovirus gastroenteritis among children in shiraz, iran

Mohammad Motamedifar et al. Iran Red Crescent Med J. 2013 Aug.

Abstract

Background: Viral pathogens are the main cause of acute gastroenteritis in developed and developing countries. Rotavirus and adenovirus are the two important agents associated with hospitalization for diarrhea especially in children. Limitation and control of diarrhea as a costly disease must be considered in national health programs.

Objectives: Epidemiological studies on viral diarrhea and collecting data for rotavirus and adenovirus prevalence, as two important viral agents of gastroenteritis, are valuable for planning of a prospective program.

Materials and methods: 827 stool samples of pediatrics patients with gastroenteritis who were admitted to Dastgheib Hospital, Shiraz, Iran, from September 2008 to February 2010 were tested for presence of rotavirus and adenovirus using the EIA method. A demographic and clinical study was performed to determine the relationship between viral infection and clinical outcomes of patients.

Results: Rotavirus was identified in 347 patients out of 827 (42%), adenovirus was detected in 76 (9%) of samples and 34 (4%) of patients had rotavirus-adenovirus co-infection. Diarrhea was the most common symptom in viral infected patients.

Conclusions: Given the non-specific symptoms of these viruses and the high prevalence of viral diarrhea in our region, more laboratories should be equipped for virus detection and vaccination might be considered as a prevention strategy.

Keywords: Adenovirus; Child; Gastroenteritis; Rotavirus.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.. Distribution of Virus-Positive Patients in Different Age Groups
Figure 2.
Figure 2.. Distribution of Rotavirus Infection, Adenovirus Infection and Co-Infection by the Month of Admission
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Bernstein DI. Rotavirus overview. Pediatr Infect Dis J. 2009;28(3 Suppl):S50–3. doi: 10.1097/INF.0b013e3181967bee. - DOI - PubMed
    1. Zeng M, Zhang Y, Zhu Q, Wang X, Yu H. Clinical and molecular epidemiology of rotavirus in children with community-acquired and hospital-acquired diarrhea in Shanghai, China. Pediatr Infect Dis J. 2010;29(2):177–80. doi: 10.1097/INF.0b013e3181ba99d4. - DOI - PubMed
    1. Subekti D, Lesmana M, Tjaniadi P, Safari N, Frazier E, Simanjuntak C, et al. Incidence of Norwalk-like viruses, rotavirus and adenovirus infection in patients with acute gastroenteritis in Jakarta, Indonesia. FEMS Immunol Med Microbiol. 2002;33(1):27–33. - PubMed
    1. Nelson EA, Bresee JS, Parashar UD, Widdowson MA, Glass RI. Rotavirus epidemiology: the Asian Rotavirus Surveillance Network. Vaccine. 2008;26(26):3192–6. doi: 10.1016/j.vaccine.2008.03.073. - DOI - PubMed
    1. Cunliffe N, Wittel D, Ngwira B. History of rotavirus research in children in Malawi: the pursuit of a killer. Malawi Med J. 2009;21(3):113–5. - PMC - PubMed

LinkOut - more resources