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Case Reports
. 2012;65(4):232-4.
doi: 10.5173/ceju.2012.04.art13. Epub 2012 Dec 11.

Metastatic malignant melanoma of the urinary bladder: Case report and literature review

Affiliations
Case Reports

Metastatic malignant melanoma of the urinary bladder: Case report and literature review

Anna Paterson et al. Cent European J Urol. 2012.

Abstract

Metastatic malignant melanoma of the urinary bladder is a rare clinical finding suggestive of advanced disease. Only 17 cases have been described in the English literature. We present a case of an 84-year-old male who was referred to the urology department with the incidental finding of bladder metastases on computed tomography (CT) one year following the diagnosis of malignant melanoma of the skin. Herein, we will discuss epidemiology, prognosis, and management options of metastatic malignant melanoma based on literature review.

Keywords: bladder metastases; hematuria; malignant melanoma.

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Figures

Fig. 1
Fig. 1
Computed Tomography scan showing multiple lesions (white arrows) within urinary bladder and a large bladder diverticulum (black arrow).
Fig. 2
Fig. 2
Cystoscopic finding of a pigmented bladder metastasis.
Fig. 3
Fig. 3
Cystoscopic finding of multiple small, pigmented bladder metastases.
Fig. 4
Fig. 4
Urine cyto 63X – Malignant melanoma cells with high N:C ratio and cytoplasmic melanin pigment on PAP stained preparation.
Fig. 5
Fig. 5
HMB-45 positive melanoma cells (large slide) and IHC-S100 positive melanoma cells (bottom right corner).

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