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Review
. 2014 Jan-Feb;66(1):73-82.
doi: 10.1016/j.ihj.2013.12.053.

The Indian Consensus Document on cardiac biomarker

I Satyamurthy  1 , Jamshed J Dalal  2 , J P S Sawhney  3 , J C Mohan  4 , Shubha A Chogle  5 , Nagaraj Desai  6 , Shireesh P Sathe  7 , Alan S Maisel  8
Affiliations
Review

The Indian Consensus Document on cardiac biomarker

I Satyamurthy et al. Indian Heart J. 2014 Jan-Feb.

Abstract

Despite recent advances, the diagnosis and management of heart failure evades the clinicians. The etiology of congestive heart failure (CHF) in the Indian scenario comprises of coronary artery disease, diabetes mellitus and hypertension. With better insights into the pathophysiology of CHF, biomarkers have evolved rapidly and received diagnostic and prognostic value. In CHF biomarkers prove as measures of the extent of pathophysiological derangement; examples include biomarkers of myocyte necrosis, myocardial remodeling, neurohormonal activation, etc. In CHF biomarkers act as indicators for the presence, degree of severity and prognosis of the disease, they may be employed in combination with the present conventional clinical assessments. These make the biomarkers feasible options against the present expensive measurements and may provide clinical benefits.

Keywords: Biomarkers; Brain natriuretic peptide; Heart failure; NT-proBNP.

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Figures

Fig. 1
Fig. 1
“Biomarker” and “Heart failure” articles published from 2001 to 2011.
Fig. 2
Fig. 2
The processing cascade of natriuretic peptides.
Fig. 3
Fig. 3
Brain natriuretic peptide interpretation in the patients with acute dyspnea without severe renal failure.
Fig. 4
Fig. 4
N-terminal proBNP interpretation in the patients with acute dyspnea without severe renal failure.
Fig. 5
Fig. 5
Galectin-3 pathway.
See this image and copyright information in PMC

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