Refractory atrial fibrillation effectively treated with ranolazine
- PMID: 24581108
- PMCID: PMC3946441
- DOI: 10.1016/j.ihj.2013.12.024
Refractory atrial fibrillation effectively treated with ranolazine
Abstract
Atrial fibrillation is the most common sustained cardiac arrhythmia which is often troublesome to manage. Currently, rhythm and rate control medications are the mainstays of therapy. In 2 amiodarone-refractory highly symptomatic patients, an innovative approach using ranolazine, which selectively acts on Na+ channels and delays atrial depolarization, was tried successfully.
Keywords: Anti-arrhythmic drugs; Arrhythmias; Cardioversion.
Copyright © 2013 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.
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References
-
- Haïssaguerre M., Jaïs P., Shah D. Spontaneous initiation of atrial fibrillation by ectopic beats originating in the pulmonary veins. N Engl J Med. 1998;339:659–666. - PubMed
-
- Fuster V., Ryden L.E., Cannom D.S. ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillation. J Am Coll Cardiol. 2006;48:149–246. - PubMed
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