Interphase chromatin LINEd with RNA
- PMID: 24581484
- DOI: 10.1016/j.cell.2014.02.005
Interphase chromatin LINEd with RNA
Abstract
RNA has been proposed to be a component of an underlying nuclear matrix. Hall et al. show that noncoding, repetitive RNAs, some derived from LINE1 elements, stably associate with interphase chromosomes and copurify with nuclear scaffold, indicating that RNAs might impact interphase chromosome architecture.
Copyright © 2014 Elsevier Inc. All rights reserved.
Comment on
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Stable C0T-1 repeat RNA is abundant and is associated with euchromatic interphase chromosomes.Cell. 2014 Feb 27;156(5):907-19. doi: 10.1016/j.cell.2014.01.042. Cell. 2014. PMID: 24581492 Free PMC article.
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