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Review
. 2014 Mar;43(1):149-66.
doi: 10.1016/j.ecl.2013.09.003.

Peripheral arterial disease

Janice V Mascarenhas  1 , Mostafa A Albayati  2 , Clifford P Shearman  2 , Edward B Jude  3
Affiliations
Review

Peripheral arterial disease

Janice V Mascarenhas et al. Endocrinol Metab Clin North Am. 2014 Mar.

Abstract

Peripheral arterial disease (PAD) is an atherosclerotic-driven condition that remains underdiagnosed and undertreated. In diabetic patients, PAD begins early, progresses rapidly, and is frequently asymptomatic, making it difficult to diagnose. Strict management of the metabolic instigators and use of screening techniques for PAD in diabetes can facilitate early diagnosis and reduce progression. Exercise is an equally effective treatment option in improving walking distance. Early revascularization must be offered early in suitable patients. Surgical bypass and endovascular revascularization are complementary and the choice of intervention should be applied appropriately by a multidisciplinary vascular team on a selective, patient-specific basis.

Keywords: Ankle brachial pressure index; Critical limb ischemia; Endothelial dysfunction; Intermittent claudication.

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