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Case Reports
. 2014 Sep;25(3):321-3.
doi: 10.1007/s12022-014-9299-6.

Ectopic prolactin-producing pituitary adenoma in a benign ovarian cystic teratoma

Saba Al-Bazzaz  1 , Jason Karamchandani, Eva Mocarski, Eva Horvath, Fabio Rotondo, Kalman Kovacs
Affiliations
Case Reports

Ectopic prolactin-producing pituitary adenoma in a benign ovarian cystic teratoma

Saba Al-Bazzaz et al. Endocr Pathol. 2014 Sep.

Abstract

We report the presence of pituitary tissue in a benign ovarian cystic teratoma removed surgically from a 43-year-old woman. The pituitary consisted of non-tumorous neurohypophysis and adenohypophysis containing mainly prolactin (PRL)-immunopositive cells (80 % of cells) and a small PRL-producing adenoma. The ultrastructure of the tumor cells differed significantly from PRL cells in the non-tumorous and adenomatous intrasellar pituitary. It appears that cells differing in ultrastructure from intrasellar pituitary PRL cells can also produce PRL.

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