Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1988 Oct;62(10):3900-2.
doi: 10.1128/JVI.62.10.3900-3902.1988.

Low fidelity of cell-free DNA synthesis by reverse transcriptase of human immunodeficiency virus

Y Takeuchi  1 , T Nagumo, H Hoshino
Affiliations

Low fidelity of cell-free DNA synthesis by reverse transcriptase of human immunodeficiency virus

Y Takeuchi et al. J Virol. 1988 Oct.

Abstract

The fidelity of DNA synthesis by reverse transcriptases from human immunodeficiency virus and other retroviruses was compared by measuring the rates of misincorporation of dCMP in the place of TMP in cell-free DNA synthesis with polyadenylic acid as the template. The fidelity of human immunodeficiency virus reverse transcriptase was found to be about one-third of that of the reverse transcriptases of other retroviruses.

PubMed Disclaimer

References

    1. J Biol Chem. 1974 Jul 10;249(13):4086-93 - PubMed
    1. Nature. 1979 Apr 26;278(5707):857-9 - PubMed
    1. J Biol Chem. 1981 Oct 10;256(19):9883-9 - PubMed
    1. Proc Natl Acad Sci U S A. 1981 Nov;78(11):6734-8 - PubMed
    1. Science. 1982 Mar 26;215(4540):1577-85 - PubMed

Publication types

LinkOut - more resources