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. 2014 Mar 4:12:50.
doi: 10.1186/1477-7819-12-50.

Surgery and outcomes of six patients with intradural epidermoid cysts in the lumbar spine

Huabin Yin, Dan Zhang, Zhipeng Wu, Wang Zhou  1 , Jianru Xiao
Affiliations

Surgery and outcomes of six patients with intradural epidermoid cysts in the lumbar spine

Huabin Yin et al. World J Surg Oncol. .

Abstract

Study design: This was a retrospective study.

Objective: The aim of this study was to analyze the clinical characteristics and discuss the treatment options for epidermoid cysts in the lumbar spine.

Summary of background data: Epidermoid cysts are rare benign neoplasms, which account for less than 1% of all intraspinal tumors. Due to their rarity, there are only a few case reports in the literature. Complete excision is the recommended treatment for an epidermoid cyst, but this is difficult to achieve in the spine. In spite of their benign nature, local recurrence is not uncommon for spinal epidermoid cysts after incomplete excision.

Methods: Six patients with an epidermoid cyst in the lumbar spine underwent surgical treatment in our center between 2004 and 2011. A total excision using microsurgical techniques and reconstruction was successfully undertaken in all patients. Clinical data and detailed pathologic results were retrospectively analyzed. All cases were followed up for a median time of more than 4 years. The clinical data and surgical efficacy were analyzed to suggest treatment options for epidermoid cysts in the lumbar spine on the basis of a literature review and our own experience.

Results: The mean age of the patients in this study was 37.7 years and the mean duration of pre-operative symptoms was 29.7 months (2 to 120 months). All patients were disease-free during their follow-up period. Radicular pain nearly disappeared, and patients suffering from neurologic deficits and defecation disorders recovered well.

Conclusions: Although an epidermoid cyst is a benign tumor, it is apt to recur locally following inadequate removal. Therefore, complete excision with preservation of neural function is an ideal protocol for intraspinal epidermoid cysts. Microsurgical techniques are very useful.

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Figures

Figure 1
Figure 1
MRI images of an epidermoid cyst with atypical imaging (case 2). (A) T2-weighted image. The epidermoid cyst was hypointense. (B) T1-weighted image. The tumor was hyperintense.
Figure 2
Figure 2
Pathology image of an intraspinal epidermoid cyst. The image shows well-differentiated stratified squamous epithelium lining the interior surface of the cyst capsule where keratin can be found.
See this image and copyright information in PMC

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