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. 2014 Nov;23(6):587-93.
doi: 10.1097/CEJ.0000000000000013.

A mortality study of workers exposed to insoluble forms of beryllium

Paolo Boffetta  1 , Tiffani Fordyce, Jack S Mandel
Affiliations

A mortality study of workers exposed to insoluble forms of beryllium

Paolo Boffetta et al. Eur J Cancer Prev. 2014 Nov.

Abstract

This study investigated lung cancer and other diseases related to insoluble beryllium compounds. A cohort of 4950 workers from four US insoluble beryllium manufacturing facilities were followed through 2009. Expected deaths were calculated using local and national rates. On the basis of local rates, all-cause mortality was significantly reduced. Mortality from lung cancer (standardized mortality ratio 96.0; 95% confidence interval 80.0, 114.3) and from nonmalignant respiratory diseases was also reduced. There were no significant trends for either cause of death according to duration of employment or time since first employment. Uterine cancer among women was the only cause of death with a significantly increased standardized mortality ratio. Five of the seven women worked in office jobs. This study confirmed the lack of an increase in mortality from lung cancer and nonmalignant respiratory diseases related to insoluble beryllium compounds.

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    Boffetta P, Fordyce TA, Mandel JS. Boffetta P, et al. Cancer Med. 2016 Dec;5(12):3596-3605. doi: 10.1002/cam4.918. Epub 2016 Oct 20. Cancer Med. 2016. PMID: 27766788 Free PMC article.

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