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Review
. 2014 Mar 3;369(1640):20130232.
doi: 10.1098/rstb.2013.0232. Print 2014 Apr 19.

Influence of plastids on light signalling and development

Robert M Larkin  1
Affiliations
Review

Influence of plastids on light signalling and development

Robert M Larkin. Philos Trans R Soc Lond B Biol Sci. .

Abstract

In addition to their contribution to metabolism, chloroplasts emit signals that influence the expression of nuclear genes that contribute to numerous plastidic and extraplastidic processes. Plastid-to-nucleus signalling optimizes chloroplast function, regulates growth and development, and affects responses to environmental cues. An incomplete list of plastid signals is available and particular plastid-to-nucleus signalling mechanisms are partially understood. The plastid-to-nucleus signalling that depends on the GENOMES UNCOUPLED (GUN) genes couples the expression of nuclear genes to the functional state of the chloroplast. Analyses of gun mutants provided insight into the mechanisms and biological functions of plastid-to-nucleus signalling. GUN genes contribute to chloroplast biogenesis, the circadian rhythm, stress tolerance, light signalling and development. Some have criticized the gun mutant screen for employing inhibitors of chloroplast biogenesis and suggested that gun alleles do not disrupt significant plastid-to-nucleus signalling mechanisms. Here, I briefly review GUN-dependent plastid-to-nucleus signalling, explain the flaws in the major criticisms of the gun mutant screen and review the influence of plastids on light signalling and development.

Keywords: development; gun mutants; light signalling; plastid-to-nucleus signalling.

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References

    1. Larkin RM, Ruckle ME. 2008. Integration of light and plastid signals. Curr. Opin. Plant Biol. 11, 593–599. (10.1104/pp.112.193599) - DOI - PubMed
    1. Mullineaux PM, Baker NR. 2010. Oxidative stress: antagonistic signaling for acclimation or cell death? Plant Physiol. 154, 521–525. (10.1104/pp.110.161406) - DOI - PMC - PubMed
    1. Chi W, Sun X, Zhang L. 2013. Intracellular signaling from plastid to nucleus. Annu. Rev. Plant Biol. 64, 559–582. (10.1146/annurev-arplant-050312-120147) - DOI - PubMed
    1. Mochizuki N, Susek R, Chory J. 1996. An intracellular signal transduction pathway between the chloroplast and nucleus is involved in de-etiolation. Plant Physiol. 112, 1465–1469. (10.1104/pp.112.4.1465) - DOI - PMC - PubMed
    1. Ruckle ME, DeMarco SM, Larkin RM. 2007. Plastid signals remodel light signaling networks and are essential for efficient chloroplast biogenesis in Arabidopsis. Plant Cell 19, 3944–3960. (10.1105/tpc.107.054312) - DOI - PMC - PubMed

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