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. 2014 Oct;69(10):951-2.
doi: 10.1136/thoraxjnl-2014-205253. Epub 2014 Mar 4.

Community-based recruitment of patients with COPD into clinical research

Simon E Brill  1 , Ethaar El-Emir  1 , James P Allinson  1 , Gavin C Donaldson  1 , Irwin Nazareth  2 , Jadwiga A Wedzicha  1
Affiliations
Free PMC article

Community-based recruitment of patients with COPD into clinical research

Simon E Brill et al. Thorax. 2014 Oct.
Free PMC article

Abstract

Identifying subjects for clinical trials is difficult and the evidence base for recruitment strategies is limited, particularly in the field of COPD. We compared the efficiency and patient characteristics of different community-based recruitment strategies during a non-commercial COPD trial in the UK. Recruiting from general practice COPD registers was less efficient and identified patients with significantly milder disease than recruiting through pulmonary rehabilitation and patient groups. We report our experience and propose that pulmonary rehabilitation and patient groups may represent an enriched pool of COPD patients to recruit into clinical trials.

Trial registration number: EudraCT 2011-001063-43.

Keywords: COPD Epidemiology; Pulmonary Rehabilitation.

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Figures

Figure 1
Figure 1
Flow diagram detailing the three different recruitment pathways.
See this image and copyright information in PMC

References

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