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Randomized Controlled Trial
. 2014 Mar 5;311(9):937-48.
doi: 10.1001/jama.2014.607.

Associations of housing mobility interventions for children in high-poverty neighborhoods with subsequent mental disorders during adolescence

Affiliations
Randomized Controlled Trial

Associations of housing mobility interventions for children in high-poverty neighborhoods with subsequent mental disorders during adolescence

Ronald C Kessler et al. JAMA. .

Retracted and republished in

Abstract

Importance: Youth in high-poverty neighborhoods have high rates of emotional problems. Understanding neighborhood influences on mental health is crucial for designing neighborhood-level interventions.

Objective: To perform an exploratory analysis of associations between housing mobility interventions for children in high-poverty neighborhoods and subsequent mental disorders during adolescence.

Design, setting, and participants: The Moving to Opportunity Demonstration from 1994 to 1998 randomized 4604 volunteer public housing families with 3689 children in high-poverty neighborhoods into 1 of 2 housing mobility intervention groups (a low-poverty voucher group vs a traditional voucher group) or a control group. The low-poverty voucher group (n=1430) received vouchers to move to low-poverty neighborhoods with enhanced mobility counseling. The traditional voucher group (n=1081) received geographically unrestricted vouchers. Controls (n=1178) received no intervention. Follow-up evaluation was performed 10 to 15 years later (June 2008-April 2010) with participants aged 13 to 19 years (0-8 years at randomization). Response rates were 86.9% to 92.9%.

Main outcomes and measures: Presence of mental disorders from the Diagnostic and Statistical Manual of Mental Disorders (Fourth Edition) within the past 12 months, including major depressive disorder, panic disorder, posttraumatic stress disorder (PTSD), oppositional-defiant disorder, intermittent explosive disorder, and conduct disorder, as assessed post hoc with a validated diagnostic interview.

Results: Of the 3689 adolescents randomized, 2872 were interviewed (1407 boys and 1465 girls). Compared with the control group, boys in the low-poverty voucher group had significantly increased rates of major depression (7.1% vs 3.5%; odds ratio (OR), 2.2 [95% CI, 1.2-3.9]), PTSD (6.2% vs 1.9%; OR, 3.4 [95% CI, 1.6-7.4]), and conduct disorder (6.4% vs 2.1%; OR, 3.1 [95% CI, 1.7-5.8]). Boys in the traditional voucher group had increased rates of PTSD compared with the control group (4.9% vs 1.9%, OR, 2.7 [95% CI, 1.2-5.8]). However, compared with the control group, girls in the traditional voucher group had decreased rates of major depression (6.5% vs 10.9%; OR, 0.6 [95% CI, 0.3-0.9]) and conduct disorder (0.3% vs 2.9%; OR, 0.1 [95% CI, 0.0-0.4]).

Conclusions and relevance: Interventions to encourage moving out of high-poverty neighborhoods were associated with increased rates of depression, PTSD, and conduct disorder among boys and reduced rates of depression and conduct disorder among girls. Better understanding of interactions among individual, family, and neighborhood risk factors is needed to guide future public housing policy changes.

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Conflict of interest statement

Conflict of Interest Disclosures: Dr. Kessler has been a consultant for AstraZeneca, Analysis Group, Bristol-Myers Squibb, Cerner-Galt Associates, Eli Lilly & Company, GlaxoSmithKline Inc., Health Core Inc., Health Dialog, Hoffman-LaRoche, Inc., Integrated Benefits Institute, J & J Wellness & Prevention, Inc., John Snow Inc., Kaiser Permanente, Lake Nona Institute, Matria Inc., Mensante, Merck & Co, Inc., Ortho-McNeil Janssen Scientific Affairs, Pfizer Inc., Primary Care Network, Research Triangle Institute, Sanofi-Aventis Groupe, Shire US Inc., SRA International, Inc., Takeda Global Research & Development, Transcept Pharmaceuticals Inc., and Wyeth-Ayerst. Dr. Kessler has served on advisory boards for Appliance Computing II, Eli Lilly & Company, Mindsite, Ortho-McNeil Janssen Scientific Affairs, Johnson & Johnson, Plus One Health Management and Wyeth-Ayerst. Dr. Kessler has had research support for his epidemiological studies from Analysis Group Inc., Bristol-Myers Squibb, Eli Lilly & Company, EPI-Q, GlaxoSmithKline, Johnson & Johnson Pharmaceuticals, Ortho-McNeil Janssen Scientific Affairs., Pfizer Inc., Sanofi-Aventis Groupe, Shire US, Inc., and Walgreens Co. Dr. Kessler owns 25% share in DataStat, Inc. Dr Gennetian has served on advisory boards for Family Self Sufficiency TWG, Administration for Children and Families; and NORC, University of Chicago. Dr Katz has served on advisory boards for Manpower Demonstration Research Corporation and the Russell Sage Foundation. Dr Ludwig serves on advisory boards (uncompensated) for UCAN (Chicago), and the Board on Children, Youth and Families IOM/NAS; and has served as a consultant for the MacArthur Foundation Network on Children and Housing and the MDRC Early Childhood Institute. The remaining authors report no conflicts of interest.

Figures

Figure
Figure. Study flow of the long-term MTO adolescent sample evaluationa
aTarget respondents for the adolescent long-term evaluation included all baseline residents of randomized MTO households who were ages 0-8 at randomization between 1994-1998, 13-17 at selection in December 2007, and 13-19 at interview between June 2008 and April 2010. All adolescents in the eligible age range who lived at baseline in households containing three or fewer youth ages 10 to 20 were targeted for follow-up, while a random three youth were targeted from baseline households with four or more youth. A weight of n/3, where n = the number of eligible youths in the baseline household, was used to adjust for the under-sampling of youths from baseline households containing more than three eligible youth. The term “Phase 1” data collection refers to the efforts made to contact and interview all target respondents until the end of the field period, at which point a random 35% of target respondents who had not yet either been interviewed, were deceased, declined to participate, or were incapacitated (incarcerated or unable to be interviewed due to a barrier related to health or language) were selected for a more intensive “Phase 2” data collection effort that included expanded tracing efforts (e.g., using private investigators to trace target respondents who had not yet been located) and increased financial incentives to obtain interviews from hard-to-recruit youths. A weight of 1/.35 was used to adjust for the under-sampling of the hard-to-recruit youths who were interviewed.

Comment in

References

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