Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2014 Jan 1:3:e02387.
doi: 10.7554/eLife.02387.

Vive la resistance!

Steven J Sandler  1
Affiliations
Comment

Vive la resistance!

Steven J Sandler. Elife. .

Abstract

In vitro evolution experiments reveal that single mutations in three genes can increase the ability of E. coli to survive ionizing radiation by a factor of 1000.

Keywords: DNA repair; evolution; extremophile; ionizing radiation; mutation.

PubMed Disclaimer

Conflict of interest statement

Competing interests:The author declares that no competing interests exist.

Comment on

References

    1. Byrne RT, Klingele AJ, Cabot EL, Schackwitz WS, Martin JA, Martin J, Wang Z, Wood EA, Pennacchio C, Pennacchio LA, Perna NT, Battista JA, Cox MM. 2014. Evolution of extreme resistance to ionizing radiation via genetic adaptation of DNA repair. eLife 3:e01322. 10.7554/eLife.01322 - DOI - PMC - PubMed
    1. Harris DR, Pollock SV, Wood EA, Goiffon RJ, Klingele AJ, Cabot EL, Schackwitz W, Martin J, Eggington J, Durfee TJ, Middle CM, Norton JE, Popelars MC, Li H, Klugman SA, Hamilton LL, Bane LB, Pennacchio LA, Albert TJ, Perna NT, Cox MM, Battista JR. 2009. Directed Evolution of radiation resistance in Escherichia coli. Journal of Bacteriology 191:5240–5252. 10.1128/JB.00502-09 - DOI - PMC - PubMed

Substances

LinkOut - more resources