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Review
. 2014 Mar;31(1):27-32.
doi: 10.1055/s-0033-1363840.

Surgical management of renal cell carcinoma

Laura-Maria Krabbe  1 , Aditya Bagrodia  2 , Vitaly Margulis  2 , Christopher G Wood  3
Affiliations
Review

Surgical management of renal cell carcinoma

Laura-Maria Krabbe et al. Semin Intervent Radiol. 2014 Mar.

Abstract

Surgical resection of renal cell carcinoma (RCC) is the benchmark for long-term cure of the disease. Although open or laparoscopic radical nephrectomy is considered the gold standard for stage T1b-T4 tumors, nephron-sparing surgery is the preferred operative modality for small renal masses demonstrating equivalent oncologic efficacy and improved renal function outcomes compared with complete nephrectomy. With the advance of minimally invasive surgery, nephron-sparing procedures can safely be conducted laparoscopically with or without robotic assistance. RCC with intravenous tumor thrombus presents a surgical challenge, but multidisciplinary surgical approaches can provide long-term benefit in these patients. The role of cytoreductive nephrectomy and metastasectomy in patients with metastatic RCC (mRCC) is controversial, but seems to be beneficial for patients in the era of targeted therapy.

Keywords: nephron-sparing surgery; radical nephrectomy; renal cell carcinoma; surgical management.

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Figures

Figure 1
Figure 1
(A) Radiologic image and (B) intraoperative view of a left renal tumor amenable to partial nephrectomy (arrow, A).
Figure 2
Figure 2
(A) Radiologic image of a tumor thrombus (arrows) and (B) a specimen including an inferior vena cava thrombus (arrow).
Figure 3
Figure 3
(A) Radiologic image of a resectable systemic metastasis (arrow) and (B) radiologic image of a resectable local recurrence (arrow).
See this image and copyright information in PMC

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