Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2014 Feb 17;4(1).
doi: 10.3402/jchimp.v4.23148. eCollection 2014.

Touch me not

Paras Karmacharya  1 , Kalpana Shah  2 , Ranjan Pathak  1 , Sushil Ghimire  3 , Richard Alweis  1
Affiliations
Case Reports

Touch me not

Paras Karmacharya et al. J Community Hosp Intern Med Perspect. .

Abstract

Central Poststroke Pain syndrome (CPSP) can occur due to disruption of the somatosensory pathways of the brain at any level such as the thalamus, medulla, or cerebral cortex. It is characterized by sensory abnormalities and hyperesthesia in the part of the body correlating to the central lesion. The treatment of this pain syndrome is often difficult, and it does not usually respond to traditional analgesics. The first line of treatment is drugs aimed at lowering neuronal hyperexcitability, for example, amitriptyline or lamotrigine, with gabapentin considered a second line.

Keywords: Central Poststroke Pain; Déjerine Roussy syndrome; gabapentin; neuropathic pain; thalamic pain syndrome.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Axial Diffusion-weighted MR image showing punctate focus of increased signal in Lt. posteroinferolateral region of thalamus (arrow).
Fig. 2
Fig. 2
Axial T2 FLAIR MR image demonstrating subacute lesion with hyperintense signal in Lt. posteroinferolateral region of thalamus (arrow).
See this image and copyright information in PMC

References

    1. Krause T, Brunecker P, Pittl S, Taskin B, Laubisch D, Winter B, et al. Thalamic sensory strokes with and without pain: Differences in lesion patterns in the ventral posterior thalamus. J Neurol Neurosurg Psychiatry. 2012;83(8):776–84. - PubMed
    1. Klit H, Finnerup NB, Jensen TS. Central post-stroke pain: Clinical characteristics, pathophysiology, and management. Lancet Neurol. 2009;8(9):857–68. - PubMed
    1. Flaster M, Meresh E, Rao M, Biller J. Central poststroke pain: Current diagnosis and treatment. Top Stroke Rehabil. 2013;20(2):116–23. - PubMed
    1. Andersen G, Vestergaard K, Ingeman-Nielsen M, Jensen TS. Incidence of central post-stroke pain. Pain. 1995;61(2):187–93. - PubMed
    1. Leijon G, Boivie J. Central post-stroke pain – a controlled trial of amitriptyline and carbamazepine. Pain. 1989;36(1):27–36. - PubMed

Publication types

LinkOut - more resources