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. 1988 Aug;78(2):115-7.
doi: 10.1111/j.1600-0404.1988.tb03631.x.

Hemiballismus: changes in cerebrospinal fluid

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Hemiballismus: changes in cerebrospinal fluid

V Kostic et al. Acta Neurol Scand. 1988 Aug.

Abstract

Concentrations of serotonin metabolite, 5-hydroxyindoleacetic acid (5-HIAA), and dopamine metabolites, homovanillic acid (HVA) and 3,4-dihydroxy-phenylacetic acid (DOPAC), were measured in the samples of cerebrospinal fluid of 5 patients with acute hemiballismus. The only significant change was the increased content of HVA compared to controls. This finding support the hypothesis on the increased dopamine turnover in hemiballismus and provide a rational basis for the present treatment with antidopaminergic agents.

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