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Review
. 2014 Feb 24:5:70.
doi: 10.3389/fimmu.2014.00070. eCollection 2014.

Beyond MyD88 and TRIF Pathways in Toll-Like Receptor Signaling

Vincent Piras  1 , Kumar Selvarajoo  1
Affiliations
Review

Beyond MyD88 and TRIF Pathways in Toll-Like Receptor Signaling

Vincent Piras et al. Front Immunol. .
No abstract available

Keywords: Pearson correlation; Toll-like receptors; gene expression; innate immunity; macrophages.

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Figures

Figure 1
Figure 1
The Toll-like receptor-4 mediated transcriptional responses in wildtype and mutant macrophages. (A) Schematic topology showing the major players of the Toll-like receptor-4 signaling. The dotted line indicates the hypothetic pathways activating the pleiotropic transcriptional response independently from the TLR4 signaling. Auto-correlations and cross-correlations for whole genome (B,C) and 157 important immune genes (D,E) in LPS-stimulated murine macrophages. x-axis represents time (in hours after LPS stimulation), and y-axis represents the correlation coefficient (with t = 0 h for auto-correlations, and between KO genotypes and wildtype for cross-correlations). Figure adapted from Ref. (2).
See this image and copyright information in PMC

References

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