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. 2014 Jan;66(1):31-4.
doi: 10.1007/s12070-013-0632-z. Epub 2013 Feb 27.

Connecticut (CCCRC) Olfactory Test: Normative Values in 426 Healthy Volunteers

Bayram Veyseller  1 , Berke Ozucer  1 , Aysegul Batioglu Karaaltin  2 , Yalcin Yildirim  1 , Nazan Degirmenci  1 , Fadlullah Aksoy  1 , Orhan Ozturan  1
Affiliations

Connecticut (CCCRC) Olfactory Test: Normative Values in 426 Healthy Volunteers

Bayram Veyseller et al. Indian J Otolaryngol Head Neck Surg. 2014 Jan.

Abstract

Application of Connecticut Chemosensory Clinical Research Center (CCCRC) olfactory test to healthy Turkish volunteers, obtain normative data set and analyse the role of age, sex and smoking on olfactory scores. The present study was conducted at Bezmialem Vakif University, Department of Otorhinolaryngology. Total of 426 healthy volunteers were subjected to CCCRC olfactory test which consists of n-butanol smell threshold test and smell identification test. Olfactory function score was assessed (0: worst score; 7: best score) and mean scores were calculated. Mean age was (36.7 ± 11.1; range, 17-68). 46.2 % of the subjects were male and 53.8 % were female; 37.1 % were smokers and 62.9 % were non-smokers. Mean n-butanol threshold score was 6.36 out of 7, mean identification score was 6.34 and mean total score was 6.35. According to CCCRC score: there were no anosmic individuals, 0.5 % were severely hyposmic, 2.6 % were moderately hyposmic,15.3 % were mildly hyposmic and 81.6 % were normosmic. CCCRC olfactory test is cost-effective, simple and practical. It can be easily applied in clinical settings. The CCCRC olfactory test is appropriate for assessment of olfactory function: Turkish population is familiar in terms of the odors used in CCCRC test. The power of this study is that it provides a normative data set against which many factors can be compared.

Keywords: CCCRC; Odor identification; Odor threshold; Olfactory dysfunction; Olfactory function; Olfactory test.

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Figures

Fig. 1
Fig. 1
Evaluation of CCCRC olfactory test scores, patient distribution (%) Normosmic: 6.00–7.00, Mildly hyposmic: 5.00–5.75, Moderately hyposmic: 4.00–4.75, Severely Hyposmic: 2.00–3.75, Anosmic: 0–1.75 (Out of 7)
Fig. 2
Fig. 2
Total CCCRC test score (out of 7, males vs. females) Female subjects scored higher compared to males but the difference was not statistically significant(p = 0.09)
Fig. 3
Fig. 3
Total CCCRC test score (out of 7, smokers vs. non-smokers) Very significant difference in terms of total CCCRC score (p = 0.0008)
Fig. 4
Fig. 4
CCCRC Scores evaluated based on decades (CCCRC Score vs. Age groups) Lower olfactory scores were observed with increased age, except for the 50–59 age group
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