Comment
doi: 10.1016/j.stem.2014.02.009.
Stress management: a new path to pluripotency
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- PMID: 24607402
- DOI: 10.1016/j.stem.2014.02.009
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Stress management: a new path to pluripotency
Cell Stem Cell.
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Abstract
Two recent papers in Nature describe a remarkable new technique for reprogramming somatic cells back to the embryonic state. Obokata et al. (2014a, 2014b) show that applying stressful stimuli can convert mature cells into progenitors capable of generating all three embryonic germ layer lineages, as well as placental tissue.
Copyright © 2014 Elsevier Inc. All rights reserved.
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Stimulus-triggered fate conversion of somatic cells into pluripotency.Nature. 2014 Jan 30;505(7485):641-7. doi: 10.1038/nature12968. Nature. 2014. Retraction in: Nature. 2014 Jul 3;511(7507):112. doi: 10.1038/nature13598. PMID: 24476887 Retracted.
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Bidirectional developmental potential in reprogrammed cells with acquired pluripotency.Nature. 2014 Jan 30;505(7485):676-80. doi: 10.1038/nature12969. Nature. 2014. Retraction in: Nature. 2014 Jul 3;511(7507):112. doi: 10.1038/nature13599. PMID: 24476891 Retracted.
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