Diagnostic criteria in proliferative verrucous leukoplakia: evaluation
- PMID: 24608210
- PMCID: PMC4119307
- DOI: 10.4317/medoral.19424
Diagnostic criteria in proliferative verrucous leukoplakia: evaluation
Abstract
Objectives: to evaluate the ability of the diagnostic criteria proposed by Cerero et al in 2010 to perform an early diagnose in patients with proliferative verrucous leukoplakia.
Study design: retrospective study with patients diagnosed with leukoplakia at Oral Medicine Service at Oral Medicine and Surgery Department at Dentistry Faculty at Universidad Complutense of Madrid.
Results: the criteria were applied in 116 patients, turning positive in 40 cases. Out of these, 24 (60%) had been previously diagnosed with PVL. Most frequent criteria were major criteria A and E, concerning lesion's site and histopathology, and minor criteria b and c, concerning sex and smoking habit.
Conclusions: diagnostic criteria developed by Cerero et al can be a useful tool for an early diagnose of PVL, as in 60% of the cases, the criteria would have allowed to make an early diagnose of the disease.
Conflict of interest statement
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References
-
- Scully C, Bagan JV, Epstein JB. Oral cancer: current and future diagnostic techniques. Am J Dent. 2008;21:199–209. - PubMed
-
- Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol. 2009;45:309–316. - PubMed
-
- Van der Waal I. Potentially malignant disorders of the oral and oropharyngeal mucosa; terminology, classification and present concepts of management. Oral Oncol. 2009;45:317–323. - PubMed
-
- Hansen LS, Olson JA, Silverman SJr. Proliferative verrucous leukoplakia. A long-term study of thirty patients. Oral Surg Oral Med Oral Pathol. 1985;60:285–298. - PubMed
-
- Silverman S Jr, Grosky M. Proliferative verrucous leukoplakia: a follow up study of 54 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1997;84:154–157. - PubMed
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