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. 2014 Mar 7;9(3):e91059.
doi: 10.1371/journal.pone.0091059. eCollection 2014.

Dental caries, prevalence and risk factors in patients with Crohn's disease

Sara Szymanska  1 , Mikael Lördal  2 , Nilminie Rathnayake  1 , Anders Gustafsson  1 , Annsofi Johannsen  1
Affiliations

Dental caries, prevalence and risk factors in patients with Crohn's disease

Sara Szymanska et al. PLoS One. .

Abstract

Objective: The present study tested the hypothesis that patients with Crohn's disease (CD) have a higher prevalence and risk for caries compared to people without CD.

Material and methods: Patients with CD were divided into groups; 71 patients (50.7 ± 13.9 years) who had gone through resective intestinal surgery and 79 patients (42.0 ± 14.4 years) who had not. The patients were compared to 75 controls (48.6 ± 13.4 years) regarding DMF-T and DMF-S, Lactobacilli (LB), Streptococcus mutans (SM), salivary flow and dental plaque. Statistical methods including ANOVA or Chi-square test for calculation of demographic differences between groups, analysis of covariance (ANCOVA) to compare the clinical variable and Post hoc analyses were done with Fischers Least Significant Difference test or Chi-square. Non-parametric Spearman's correlation matrix coefficient was estimated between clinical variables and disease duration.

Results: CD patients who had been subjected to resective surgery had a higher DMF-S score (50.7 versus 36.5; p = 0.01) compared to the control group after adjusting for age, gender and smoking. These patients had higher counts of SM (1.5 versus 0.9; p = 0.04) and LB (10000.0 versus 1000.0; p = 0.01), and more dental plaque (53.7 versus 22.6; p = 0.001). CD patients reported a more frequent consumption of sweetened drinks between meals compared to controls (p = 0.001).

Conclusions: The present study shows that patients with CD who had undergone resective surgery had a higher DMFs score, and higher salivary counts of Lactobacilli and Streptococcus mutans compared to the control group.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

References

    1. Head K, Jurenka JS (2004) Inflammatory bowel disease, Part ii: Crohn’s disease–pathophysiology and conventional and alternative treatment options. Altern med Rev 9: 360–401. - PubMed
    1. Crohn Bb GLOG (1932) Regional ileitis: A pathologic and clinical entity. JAMA: The Journal of the American Medical Association 99: 1323–1329.
    1. Stange EF, Travis SP, Vermeire S, Beglinger C, Kupcinkas L, et al. (2006) Organisation ECsaC: European evidence based consensus on the diagnosis and management of crohn’s disease: Definitions and diagnosis. Gut 55 Suppl 1i1–15. - PMC - PubMed
    1. Fatahzadeh M (2009) Inflammatory bowel disease. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108: e1–10. - PubMed
    1. Katz JA (2007) Management of inflammatory bowel disease in adults. J Dig Dis 8: 65–71. - PubMed

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