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Comment
. 2014 Mar 10;211(3):384.
doi: 10.1084/jem.2113insight1.

Effective double whammy targets DNA synthesis in leukemia

Bruce A Chabner  1
Affiliations
Comment

Effective double whammy targets DNA synthesis in leukemia

Bruce A Chabner. J Exp Med. .
No abstract available

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Insight from Bruce Chabner
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Deoxycytidine triphosphate can be produced by both the de novo pathway and the nucleotide salvage pathway. Image enhanced by Simon Fenwick
See this image and copyright information in PMC

Comment on

  • Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication.
    Nathanson DA, Armijo AL, Tom M, Li Z, Dimitrova E, Austin WR, Nomme J, Campbell DO, Ta L, Le TM, Lee JT, Darvish R, Gordin A, Wei L, Liao HI, Wilks M, Martin C, Sadeghi S, Murphy JM, Boulos N, Phelps ME, Faull KF, Herschman HR, Jung ME, Czernin J, Lavie A, Radu CG. Nathanson DA, et al. J Exp Med. 2014 Mar 10;211(3):473-86. doi: 10.1084/jem.20131738. Epub 2014 Feb 24. J Exp Med. 2014. PMID: 24567448 Free PMC article.

References

    1. Nathanson D.A., et al. . 2014. J. Exp. Med. 10.1084/jem.20131738. - DOI - PubMed

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