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Case Reports
. 1988;16(6):378-80.
doi: 10.1002/mpo.2950160605.

Procarbazine hypersensitivity manifested as a fixed drug eruption

J K Giguere  1 , D M Douglas, G P Lupton, J R Baker, R B Weiss
Affiliations
Case Reports

Procarbazine hypersensitivity manifested as a fixed drug eruption

J K Giguere et al. Med Pediatr Oncol. 1988.

Abstract

A case of a previously unrecognized form of hypersensitivity to procarbazine characterized by a nonpigmented fixed drug eruption is reported. Despite skin testing, association of the skin lesion to procarbazine could be determined only by drug rechallenge. Various aspects of procarbazine hypersensitivity reactions as well as the pathogenesis and importance of the fixed drug eruption are discussed.

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