Maladapted endothelial cells flip the mesenchymal switch
- PMID: 24622512
- DOI: 10.1126/scitranslmed.3008623
Maladapted endothelial cells flip the mesenchymal switch
Abstract
Endothelial cells in the neointima undergo a transition to the mesenchymal phenotype, suggesting a therapeutic target for vein graft restenosis (Cooley et al., this issue).
Comment on
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TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling.Sci Transl Med. 2014 Mar 12;6(227):227ra34. doi: 10.1126/scitranslmed.3006927. Sci Transl Med. 2014. PMID: 24622514 Free PMC article.
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