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. 2014 Aug;39(4):770-5.
doi: 10.1007/s00261-014-0116-y.

3T magnetic resonance diffusion tensor imaging in chronic kidney disease

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3T magnetic resonance diffusion tensor imaging in chronic kidney disease

Wen-juan Wang et al. Abdom Imaging. 2014 Aug.

Abstract

Objective: To investigate the relationship of apparent diffusion coefficient (ADC) and fractional anisotropy (FA) values with renal function on 3T diffusion tensor imaging (DTI) in chronic kidney disease.

Materials and methods: Twenty healthy volunteers and 29 patients with CKD underwent DTI. The relationship among ADC, FA, and renal function was analyzed.

Results: Cortical and medullary ADC and FA values of patients with chronic kidney disease were lower than those of healthy volunteers (P = 0.000). Both the renal ADC and FA values correlated inversely with serum creatinine and blood urea nitrogen (P < 0.05).

Conclusion: DTI is a feasible and non-invasive means to reflect the severity of renal function damaged.

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