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. 1988;307(3):99-104.

[Restoration, by glycine betaine, of growth and enzyme activities of Escherichia coli Lac-mutants]

[Article in French]
T Bernard  1 , M Ayache, D Le Rudulier
Affiliations
  • PMID: 2462461

[Restoration, by glycine betaine, of growth and enzyme activities of Escherichia coli Lac-mutants]

[Article in French]
T Bernard et al. C R Acad Sci III. 1988.

Abstract

Lac- mutants of Escherichia coli which presented a growth triggered by adding glycine betaine to the medium were isolated and characterized. Glycine betaine restores beta-galactosidase (strain AM 12) and lactose permease (strain AT42) activities. It is suggested that the right and active conformation of these enzymes, lost during mutagenesis, is restored, in vivo, in presence of this betaine.

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