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Review
. 2014 Jan-Feb;80(1):78-85.
doi: 10.5935/1808-8694.20140015.

Oral manifestations resulting from chemotherapy in children with acute lymphoblastic leukemia

[Article in English, Portuguese]
Everton Freitas de Morais  1 , Jadson Alexandre da Silva Lira  1 , Rômulo Augusto de Paiva Macedo  1 , Klaus Steyllon dos Santos  1 , Cassandra Teixeira Valle Elias  2 , Maria de Lourdes Silva de Arruda Morais  1
Affiliations
Review

Oral manifestations resulting from chemotherapy in children with acute lymphoblastic leukemia

[Article in English, Portuguese]
Everton Freitas de Morais et al. Braz J Otorhinolaryngol. 2014 Jan-Feb.

Abstract

Introduction: Acute lymphocytic leukemia is a type of cancer most common in children and it is characterized by excessive and disordered immature leukocytes in the bone marrow.

Aim: Identify most frequent oral manifestations in children with acute lymphocytic leukemia under chemotherapy treatment.

Methodology: The research was conducted on the electronic database PubMed/Medline, Science Direct, Scielo and Scopus. It has been sought papers with full presentation, wrote in Portuguese, English and Spanish, published between January 1992 and April 2013.

Results: From studies primarily selected, only eight met the criteria of inclusion. All studies performed intraoral examinations to diagnose oral lesions. According to results, the most frequent lesions were mucositis, candidiasis, periodontitis and gingivitis. The oral health condition from acute lymphocytic leukemia carriers varied according oral hygiene of the patient.

Conclusion: The results of studies identified such a great part of patients with ALL presented some lesion in oral cavity during or after chemotherapy treatment. The dentist surgeon needs to recognize oral manifestations and intervene in the oral health of patients with ALL, contributing and helping with treatment.

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References

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