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Comment
. 2014 Mar 12;15(3):251-2.
doi: 10.1016/j.chom.2014.02.014.

Is the intestinal goblet cell a major immune cell?

Malin E V Johansson  1 , Gunnar C Hansson  2
Affiliations
Comment

Is the intestinal goblet cell a major immune cell?

Malin E V Johansson et al. Cell Host Microbe. .

Abstract

Recent reports indicate that both the inflammasome (Wlodarska et al., 2014) and autophagy (Patel et al., 2013) pathways in goblet cells control mucin secretion, defects in which are linked to difficulties in clearing pathogenic bacteria and maintaining intestinal homeostasis and control colitis.

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Figures

Figure 1
Figure 1. A Goblet Cell Filled with MUC2 Mucin Undergoing Normal Exocystosis
Mucin is green; nucleus is in blue.
See this image and copyright information in PMC

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References

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