Water extract of the fungi from Fuzhuan brick tea improves the beneficial function on inhibiting fat deposition

Abstract

Fuzhuan brick tea (FBT) is traditionally consumed by the ethnic group in the border region of northwest China. The unique yellow fungal (Eurotium cristatum) growth phase is considered to be the key process point in the manufacture of the brick tea. The fungi from FBT are not only strongly correlated to the quality of brick tea, but also have the potential function of preventing obesity. The water extract of fungi (100 μg/mL) can significantly inhibit fat deposition in 3T3-L1 adipocyte and Caenorhabditis elegans. Furthermore, the inhibition of 3T3-L1 adipocyte formation was not due to the suppression on cell viability.

Keywords: 3T3-L1 preadipocyte; Caenorhabditis elegans; Eurotium cristatum; Fuzhuan brick tea; fat deposition.